Do Lubricants Affect Pregnancy Chances? Many couples wonder if lubricants can prevent conception. Oil based lubricants (like Vaseline, coconut oil, creams, lotions) can slow down sperm movement and reduce pregnancy chances. Sexual Lubricants: Materials and Best Uses Sexual Health Alliance Yes, It's Typically Safe To Use Coconut Oil as LubeBut There's A Catch theSkimm Have u used any natural lubricant while conception??, Coconut oil is a non toxic, sperm friendly lubricant for intercourse. It helps decrease vaginal dryness, pain during intercourse, and will not