Do electronic cigarettes create thirdhand chemical residue? Thirdhand Smoke Resource Center Does Vaping Weed Smell? The Truth About Cannabis Vape Pens Indoors Have you ever breathed in secondhand vapor from a vape? What exactly are you inhaling? It turns out it's a lengthy list of chemicals. FULL STORY Vaping releases toxic chemicals, including heavy metals, as well as ultrafine particles that go deep into the lungs. These increase the risk of heart and lung disorders.