Vaping can have serious negative impacts on both your lungs and your overall health. Here are the potential risks that we already know about, even if the vape is nicotine free: What Does Vaping Do to Your Lungs? Johns Hopkins Medicine Vaping Safe. Dr Arvind Kumar, FounderTrustee, Lung Care Foundation, warns that e cigarettes can cause severe lung injury, pneumonia, and even lead to lung transplant. He sees these cases firsthand, often in The Impact of E Cigarettes and Asthma: What You Need to Know