Vaping Versus Smoking: Are Electronic Cigarettes the Savior? Arteriosclerosis, Thrombosis, and Vascular Biology Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published Vaping may be perceived as a safer alternative to smoking cigarettesbut the heart tells a different story. Nicotine raises heart rate and blood pressure Chemicals in e cigarette aerosol can damage Impact of electronic cigarette use on blood pressure: A systematic review ScienceDirect